Article
Factor V Leiden mutation: a treatable etiology for sporadic and recurrent pregnancy loss.
Fertility and sterility - 1 Feb 2008
Glueck Charles J, Gogenini Srikant, Munjal Jitender, Tracy Trent, Pranikoff Joel, Wang Ping
Abstract excerpt
OBJECTIVE: We hypothesized that the thrombophilic G1691A factor V Leiden (FVL) gene mutation was a common, significant, and treatable cause of sporadic and recurrent pregnancy loss (RPL). DESIGN: We compared the frequency of the FVL mutation in 141 women with >or=1 pregnancy and 1 sporadic pregnancy loss (308 live births, 141 pregnancy losses), 44 women with >or=1 pregnancy and >or=3 pregnancy losses (105 live...
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