Article
The quantitative genetics of transcription.
Trends in genetics : TIG - 1 Nov 2005
Gibson Greg, Weir Bruce
Abstract excerpt
Quantitative geneticists have become interested in the heritability of transcription and detection of expression quantitative trait loci (eQTLs). Linkage mapping methods have identified major-effect eQTLs for some transcripts and have shown that regulatory polymorphisms in cis and in trans affect expression. It is also clear that these mapping strategies have little power to detect polygenic factors, and some new...
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