Article
Pregnancy associated hormones modulate the cytokine production but not the phenotype of PBMC-derived human dendritic cells.
European journal of obstetrics, gynecology, and reproductive biology - 1 Sept 2005
Huck Barbara, Steck Thomas, Habersack Marion, Dietl Johannes, Kämmerer Ulrike
Abstract excerpt
OBJECTIVE: Dendritic cells (DC) play a central role in initiating and polarizing immune responses. As effects of pregnancy associated hormones on phenotype and function of DC are unknown, our objective was to test the influence of progesterone, beta-estradiol and betaHCG on immature (iDC) and mature (mDC) DC. STUDY DESIGN: DC generated from peripheral-blood-monocytes were exposed to different doses of hormones....
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