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Article

Human Decidual Stromal Cells in Early Pregnancy Induce Functional Re-Programming of Monocyte-Derived Dendritic Cells via Crosstalk Between G-CSF and IL-1β.

Frontiers in immunology - 1 Jan 2020

Shao Qianqian, Liu Xin, Huang Yufei, Chen Xi, Wang Huayang

Abstract excerpt

Accumulation of dendritic cells (DCs) is a special characteristic of the decidual microenvironment. Decidua-infiltrated DCs show unique phenotypes and functions that promote the establishment of fetal-maternal tolerance. However, the regulatory mechanisms yet to be fully investigated. Decidual stromal cells (DSCs) are the major cellular component of decidua tissue. The interactions between DSCs and...

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Identifiers

PMID: 33193360
DOI: 10.3389/fimmu.2020.574270
PMCID: PMC7652738

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