Article
Lineage, maturity, and phenotype of uterine murine dendritic cells throughout gestation indicate a protective role in maintaining pregnancy.
Biology of reproduction - 1 Apr 2004
Blois Sandra M, Alba Soto Catalina D, Tometten Mareike, Klapp Burghard F, Margni Ricardo A, Arck Petra C
Abstract excerpt
Dendritic cells (DCs) are known to play a major role in the induction, maintenance, and regulation of immune responses. Recently, DCs have been described to be present at the feto-maternal interface in human decidua. However, only limited information is available about DC presence, phenotype, and--more importantly--function throughout gestation. Thus, we analyzed local (uterine) and systemic (blood) DCs in a...
Topics
- Animals
- Bone Marrow Cells
- CD11c Antigen
- Cell Line
- Cellular Senescence
- Dendritic Cells
- Female
- Histocompatibility Antigens Class II
- Lymphoid Tissue
- Mice
- Mice, Inbred CBA
- Mice, Inbred DBA
- Phenotype
- Pregnancy