Article
The amino-terminal residue of glycoprotein B is critical for neutralization of bovine herpesvirus 1.
Virus research - 1 Feb 2006
Okazaki Katsunori, Fujii Sanae, Takada Ayato, Kida Hiroshi
Abstract excerpt
In order to address the neutralization epitope on bovine herpesvirus 1 (BHV1) glycoprotein B (gB), a panel of monoclonal antibodies (MAbs), a series of truncation forms of the glycoprotein and an MAb-escape mutant were used in this study. Immunocytochemistry on the truncations using MAbs against the glycoprotein revealed that the neutralization epitopes recognized by the MAbs lay between residues 1 and 52 of...
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