Article
Mapping of 10 epitopes on bovine herpesvirus type 1 glycoproteins gI and gIII.
Virology - 1 May 1990
Fitzpatrick D R, Redmond M J, Attah-Poku S K, van Drunen Littel-van den Hurk S, Babiuk L A, Zamb T J
Abstract excerpt
In order to map some of the immunologically important sites on bovine herpesvirus type 1 (BHV-1), deleted, truncated, and hybrid forms of glycoproteins gI and gIII were expressed in transfected murine LMTK- cells. The cells were tested for reactivity with a panel of 16 gI- or gIII-specific monoclonal antibodies (MAbs) possessing conformation-independent antigen binding properties. This panel represented five...
Topics
- Animals
- Antibodies, Monoclonal
- Cells, Cultured
- Chromosome Mapping
- Cloning, Molecular
- Epitopes
- Herpesvirus 1, Bovine
- Models, Biological
- Mutation
- Protein Conformation
- Rats
