Article
Simultaneous mapping of epistatic QTL in DU6i x DBA/2 mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jul 2005
Carlborg Orjan, Brockmann Gudrun A, Haley Chris S
Abstract excerpt
We have mapped epistatic quantitative trait loci (QTL) in an F2 cross between DU6i x DBA/2 mice. By including these epistatic QTL and their interaction parameters in the genetic model, we were able to increase the genetic variance explained substantially (8.8%-128.3%) for several growth and body composition traits. We used an analysis method based on a simultaneous search for epistatic QTL pairs without assuming...
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