Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tetracycline-Inducible Viral Interleukin-10 Intraocular Gene Transfer, Using Adeno-Associated Virus in Experimental Autoimmune Uveoretinitis

1 Sept 2005

Abstract excerpt

Members of the adeno-associated virus (AAV) family are good candidates for the treatment of ocular diseases because of their relative lack of pathogenicity. We studied the effect of intraocular injection of AAV2-viral IL-10 (vIL-10) on retinal S-antigen-induced experimental autoimmune uveoretinitis (EAU) in Lewis rats. We demonstrated that AAV2/2-GFP injected into the vitreous body transduced the iris and ciliary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Ocular Diseases and Behçet’s Syndrome
Share to Retinal and Optic Conditions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16149902
DOI: 10.1089/hum.2005.16.1037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tetracycline-Inducible Viral Interleukin-10 Intraocular Gene Transfer, Using Adeno-Associated Virus in Experimental Autoimmune UveoretinitisPMID 16149902Read ↗

Tetracycline-Inducible Interleukin-10 Gene Transfer Mediated by an Adeno-Associated Virus: Application to Experimental ArthritisSemantic proximity Read ↗

Immunology of AAV-Mediated Gene Transfer in the EyeSemantic proximity Read ↗

AAV-delivered CRISPR-Cas9 elicits persistent retinal immune responses compared with transient responses to RNPSemantic proximity Read ↗

IFN-γ Increases the Severity and Accelerates the Onset of Experimental Autoimmune Uveitis in Transgenic RatsSemantic proximity Read ↗

Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat.Semantic proximity Read ↗

Ocular Inflammatory Response to Intravitreal Injection of Adeno-Associated Virus Vector: Relative Contribution of Genome and CapsidSemantic proximity Read ↗

AAV-mediated expression of HLA-G1/5 reduces severity of experimental autoimmune uveitisSemantic proximity Read ↗

Cellular Immune Responses Induced by Subretinal AAV Gene Transfer can be Restrained by the Subretinal Associated Immune Inhibition MechanismSemantic proximity Read ↗

Direct Adenoviral Gene Transfer of Viral IL-10 to Rabbit Knees with Experimental Arthritis Ameliorates Disease in Both Injected and Contralateral Control KneesSemantic proximity Read ↗

Intraocular injection of tamoxifen‐loaded nanoparticles: a new treatment of experimental autoimmune uveoretinitisSemantic proximity Read ↗

Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cellsSemantic proximity Read ↗

Inter-individual variability in immune responses to AAV-mediated ocular gene delivery across species impedes reliable immunomonitoring profileSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.