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Article

Association of transforming growth factor-beta1 gene polymorphism with reflux nephropathy.

The Journal of urology - 1 Oct 2005

Solari Valeria, Owen Dwight, Puri Prem

Abstract excerpt

PURPOSE: Reflux nephropathy (RN) is recognized as a major cause of end stage renal failure in children and young adults. Transforming growth factor-beta1 (TGF-beta1) is a potent proinflammatory and fibrogenetic cytokine known to have a key role in the regulation of renal tissue fibrosis. We investigate genotype frequencies for polymorphisms of the TGF-beta1 gene at position -509, codon 10 and 25, and examine...

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Identifiers

PMID: 16148664
DOI: 10.1097/01.ju.0000179385.64585.dc

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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