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Article

Role of TGF-beta1 in renal parenchymal scarring following childhood urinary tract infection.

Kidney international - 1 Jan 2002

Cotton Shirley A, Gbadegesin Rasheed A, Williams Shelley, Brenchley Paul E C, Webb Nicholas J A

Abstract excerpt

BACKGROUND: Significant variability exists in the outcome of renal parenchymal inflammation following urinary tract infection (UTI) in childhood as some children experience renal parenchymal scarring (RPS) while others do not scar. Since TGF-beta1 is pro-fibrotic, we examined the role of this cytokine in RPS following UTI. METHODS: Five polymorphisms of the TGF-beta1 gene were investigated as well as the...

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Source

Identifiers

PMID: 11786085
DOI: 10.1046/j.1523-1755.2002.00110.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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