Article
Association of transforming growth factor-beta1 gene polymorphism with familial vesicoureteral reflux.
The Journal of urology - 1 Oct 2007
Kuroda Seika, Solari Valeria, Puri Prem
Abstract excerpt
PURPOSE: Familial clustering of vesicoureteral reflux suggests that genetic factors have an important role in the pathogenesis of vesicoureteral reflux. Transforming growth factor-beta1 is a multifunctional peptide that controls proliferation and differentiation in many cell types. Recently an association between the transforming growth factor-beta1 -509 and +869 gene polymorphism, and renal parenchymal scarring...
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