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In the Wnt-er of life: Wnt signalling in melanoma and ageing

20 Oct 2016

Abstract excerpt

Although the clinical landscape of melanoma is improving rapidly, metastatic melanoma remains a deadly disease. Age remains one of the greatest risk factors for melanoma, and patients older than 55 have a much poorer prognosis than younger individuals, even when the data are controlled for grade and stage. The reasons for this disparity have not been fully uncovered, but there is some recent evidence that Wnt...

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PMID: 27764844
DOI: 10.1038/bjc.2016.332

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