Article
Rapid switching to multiple antigenic and adhesive phenotypes in malaria.
Nature - 25 Jun 1992
Roberts D J, Craig A G, Berendt A R, Pinches R, Nash G, Marsh K, Newbold C I
Abstract excerpt
Adhesion of parasitized erythrocytes to post-capillary venular endothelium or uninfected red cells is strongly implicated in the pathogenesis of severe Plasmodium falciparum malaria. Neoantigens at the infected red-cell surface adhere to a variety of host receptors, demonstrate serological diversity in field isolates and may also be a target of the host-protective immune response. Here we use sequential cloning...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
