Article
Variant antigens and endothelial receptor adhesion in Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America - 16 Apr 1996
Gardner J P, Pinches R A, Roberts D J, Newbold C I
Abstract excerpt
Parasite-derived proteins expressed on the surface of erythrocytes infected with Plasmodium falciparum are important virulence factors, since they mediate binding of infected cells to diverse receptors on vascular endothelium and are targets of a protective immune response. They are difficult to...
Topics
- Animals
- Antigenic Variation
- Antigens, Protozoan
- CD36 Antigens
- Cell Adhesion
- Endopeptidases
- Endothelium, Vascular
- Erythrocyte Aggregation
- Erythrocytes
- Humans
- In Vitro Techniques
- Intercellular Adhesion Molecule-1
