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Article

Variant antigens and endothelial receptor adhesion in Plasmodium falciparum.

Proceedings of the National Academy of Sciences of the United States of America - 16 Apr 1996

Gardner J P, Pinches R A, Roberts D J, Newbold C I

Abstract excerpt

Parasite-derived proteins expressed on the surface of erythrocytes infected with Plasmodium falciparum are important virulence factors, since they mediate binding of infected cells to diverse receptors on vascular endothelium and are targets of a protective immune response. They are difficult to study because they undergo rapid clonal antigenic variation in vitro, which precludes the derivation of phenotypically...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8622966
DOI: 10.1073/pnas.93.8.3503
PMCID: PMC39639

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