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Article

A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing.

BMC evolutionary biology - 30 Apr 2010

Shimada Makoto K, Hayakawa Yosuke, Takeda Jun-ichi, Gojobori Takashi, Imanishi Tadashi

Abstract excerpt

BACKGROUND: Alternative splicing (AS) is a key molecular process that endows biological functions with diversity and complexity. Generally, functional redundancy leads to the generation of new functions through relaxation of selective pressure in evolution, as exemplified by duplicated genes. It...

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Identifiers

PMID: 20433709
DOI: 10.1186/1471-2148-10-122
PMCID: PMC2882926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20433709-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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