Article
Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification.
Genes & development - 1 Sept 2005
Howard Beatrice, Panchal Heena, McCarthy Afshan, Ashworth Alan
Abstract excerpt
The mouse scaramanga (ska) mutation impairs mammary gland development such that both abrogation and stimulation of gland formation occurs. We used positional cloning to narrow the interval containing scaramanga (ska) to a 75.6-kb interval containing the distal part of the Neuregulin3 (Nrg3) gene. Within this region the only sequence difference between ska and wild-type mice is in a microsatellite repeat within...
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