Article
Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages.
Nature cell biology - 1 May 2013
Šale Sanja, Lafkas Daniel, Artavanis-Tsakonas Spyros
Abstract excerpt
Notch signalling is implicated in stem and progenitor cell fate control in numerous organs. Using conditional in vivo genetic labelling we traced the fate of cells expressing the Notch2 receptor paralogue and uncovered the existence of two previously unrecognized mammary epithelial cell lineages that we term S (Small) and L (Large). S cells appear in a bead-on-a-string formation and are embedded between the...
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