Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Novel p53 Target Genes in Ionizing Radiation Response

1 Sept 2005

Abstract excerpt

The tumor suppressor p53 plays an essential role in cellular adaptation to stress. In response to ionizing radiation, p53 regulates the transcription of genes in a diverse set of pathways including DNA repair, cell cycle arrest, and apoptosis. Previously, we identified by microarray analysis a set of genes that are transcriptionally activated or repressed in response to radiation exposure. In this study, we use...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cancer Research and Treatments
Share to Molecular Biology Techniques and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16140933
DOI: 10.1158/0008-5472.can-05-1039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Novel p53 Target Genes in Ionizing Radiation ResponsePMID 16140933Read ↗

Transcriptional modulation induced by ionizing radiation: p53 remains a central playerSemantic proximity Read ↗

Role of p53 in Regulating Radiation ResponsesSemantic proximity Read ↗

Genome-wide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo.Semantic proximity Read ↗

Chromatin Immunoprecipitation-Based Screen To Identify Functional Genomic Binding Sites for Sequence-Specific TransactivatorsSemantic proximity Read ↗

Genome-wide analysis of p53 under hypoxic conditions.Semantic proximity Read ↗

RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiationSemantic proximity Read ↗

Dose-dependent expression changes of early response genes to ionizing radiation in human lymphoblastoid cellsSemantic proximity Read ↗

Genetic analysis of radiation-induced changes in human gene expression.Semantic proximity Read ↗

Isolation and characterization of fourteen novel putative and nine known target genes of the p53 family.Semantic proximity Read ↗

Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.Semantic proximity Read ↗

Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damageSemantic proximity Read ↗

Whole-genome cartography of p53 response elements ranked on transactivation potentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.