Article
Genetic analysis of radiation-induced changes in human gene expression.
Nature - 28 May 2009
Smirnov Denis A, Morley Michael, Shin Eunice, Spielman Richard S, Cheung Vivian G
Abstract excerpt
Humans are exposed to radiation through the environment and in medical settings. To deal with radiation-induced damage, cells mount complex responses that rely on changes in gene expression. These gene expression responses differ greatly between individuals and contribute to individual differences in response to radiation. Here we identify regulators that influence expression levels of radiation-responsive genes....
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