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Article

Molecular Footprint of Drug-Selective Pressure in a Human Immunodeficiency Virus Transmission Chain

1 Sept 2005

Abstract excerpt

Known human immunodeficiency virus (HIV) transmission histories are invaluable models for investigating the evolutionary and transmission dynamics of the virus and to assess the accuracy of phylogenetic reconstructions. Here we have characterized an HIV-1 transmission chain consisting of nine infected patients, almost all of whom were treated with antiviral drugs at later stages of infection. Partial pol and env...

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PMID: 16140774
DOI: 10.1128/jvi.79.18.11981-11989.2005

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