Article
HIV-1 pol gene variation is sufficient for reconstruction of transmissions in the era of antiretroviral therapy.
AIDS (London, England) - 26 Mar 2004
Hué Stéphane, Clewley Jonathan P, Cane Patricia A, Pillay Deenan
Abstract excerpt
OBJECTIVES: We wished to assess the potential of using HIV-1 pol gene for the identification of transmissions events by phylogenetic means in the era of antiretroviral drug selective pressure. DESIGN: The relatedness of the viruses within a large database of pol sequences generated from HIV-1 infected individuals from the UK was reconstructed by phylogenetic analyses. METHODS: A total of 140 pol sequences were...
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