Article
Decreased virus population diversity in p53-null mice infected with weakly oncogenic Abelson virus.
Journal of virology - 1 Sept 2005
Marchlik Erica, Kalman Richard, Rosenberg Naomi
Abstract excerpt
The Abelson murine leukemia virus (Ab-MLV), like other retroviruses that contain v-onc genes, arose following a recombination event between a replicating retrovirus and a cellular oncogene. Although experimentally validated models have been presented to address the mechanism by which oncogene capture occurs, very little is known about the events that influence emerging viruses following the recombination event...
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