Article
No implication of brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: evidence from Belgian first and replication patient-control studies.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2005
Oswald Pierre, Del-Favero Jurgen, Massat Isabelle, Souery Daniel, Claes Stephan, Van Broeckhoven Christine, Mendlewicz Julien
Abstract excerpt
Several lines of evidence have suggested an implication of brain-derived neurotrophic factor (BDNF) in unipolar affective disorder (UPAD). In the present study, we investigated the role of BDNF gene in UPAD in two independent samples of 92 patients/92 controls and 156 patients/197 controls. Two single nucleotide polymorphisms (SNPs) were investigated. We found no significant differences of BDNF gene SNPs...
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