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Article

Association of the macrophage migration inhibitory factor -173*C allele with childhood nephrotic syndrome.

Pediatric nephrology (Berlin, Germany) - 1 May 2008

Vivarelli Marina, D'Urbano Leila Emma, Stringini Gilda, Ghiggeri Gian Marco, Caridi Gianluca, Donn Rachelle, Tozzi Alberto, Emma Francesco, De Benedetti Fabrizio

Abstract excerpt

Macrophage migration inflammatory factor (MIF) is a proinflammatory cytokine with a unique role as the physiologic counterregulator of the immunosuppressive effects of glucocorticoids. MIF has been implicated in the pathogenesis of glomerular inflammation. The MIF promoter contains a G/C polymorphism that is functionally relevant, with the C allele being associated with higher MIF production and linked to...

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Source

Identifiers

PMID: 18228042
DOI: 10.1007/s00467-007-0729-2

Genes

MIF
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of the macrophage migration inhibitory factor -173*C allele with childhood nephrotic syndrome.PMID 18228042Read ↗

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