Article
Implication of genetic variations in congenital obstructive nephropathy.
Pediatric nephrology (Berlin, Germany) - 1 Nov 2005
Hahn Hyewon, Ku So-Eun, Kim Kun-Suk, Park Young-Seo, Yoon Chong-Hyun, Cheong Hae-Il
Abstract excerpt
The renin-angiotensin system (RAS) has long been implicated in kidney development, and it has been reported that disruption of angiotensin type 2 receptor (AGTR2) results in a wide range of congenital anomalies of the kidney and urinary tract. We investigated the allele frequencies of the AGTR2 and other RAS genes in Korean patients with ureteropelvic junction obstruction, multicystic dysplastic kidney (MCDK),...
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