Article
Lack of Association Between Polymorphisms in AGT and ATR1 and IgA Nephropathy in a Chinese Population.
Genetic testing and molecular biomarkers - 1 Dec 2015
Gao Jie, Yu Qiao-Ling, Fu Rong-Guo, Wei Lin-Ting, Wang Meng, Dong Feng-Ming, Wang Zhe, Yang Peng-Tao, Liu Xing-Han, Dai Zhi-Jun
Abstract excerpt
OBJECTIVE: The mechanism of immunoglobulin A nephropathy (IgAN) remains unclear. Genetic factors may be associated with the risk of IgAN. This study aims to identify the possible association of M268T (rs699) in the Angiotensinogen (AGT) gene and A1166C (rs5186) in the Angiotensin II receptor type 1 (ATR1) gene with IgAN risk. METHODS: Study subjects included 351 patients with IgAN and 310 controls from the...
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