Article
Association of angiotensin type 2 receptor gene polymorphisms with ureteropelvic junction obstruction in Brazilian patients.
Nephrology (Carlton, Vic.) - 1 Nov 2014
Miranda Debora M, Dos Santos Augusto Cesar, Sarubi Helena C, Bastos-Rodrigues Luciana, Rosa Daniela Valadão, Freitas Izabella S, De Marco Luiz Armando, Oliveira Eduardo A, Simões e Silva Ana Cristina
Abstract excerpt
AIM: The angiotensin type 2 (AT2 ) receptor takes part in the process of ureteric bud during kidney development. Therefore, the gene encoding AT2 receptor, the AGTR2 gene located in the X chromosome, is a potential candidate for genetic association with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT). This study aimed to investigate whether AGTR2 gene polymorphisms are associated with CAKUT in...
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