Article
A-20C angiotensinogen gene polymorphism and proteinuria in childhood IgA nephropathy.
Pediatric nephrology (Berlin, Germany) - 1 Feb 2004
Nakanishi Koichi, Sako Mayumi, Yata Nahoko, Aoyagi Noriyuki, Nozu Kandai, Tanaka Ryojiro, Iijima Kazumoto, Yoshikawa Norishige
Abstract excerpt
We have previously reported that the TT genotype of the angiotensinogen gene and the ID/DD genotype of the angiotensin-converting enzyme gene are associated with increased severity of proteinuria in IgA nephropathy in Japanese children. Recently it was reported that polymorphism at -20 from adenine to cytosine in the angiotensinogen gene, increasing the level of this transcript, was associated with the...
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