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Article

Sequence variants in the renin-angiotensin system genes are associated with isolated multicystic dysplastic kidney in children.

Pediatric research - 1 Jul 2021

Song Renfang, Yosypiv Ihor V

Abstract excerpt

BACKGROUND: Multicystic dysplastic kidney (MCDK) is a common form of congenital cystic kidney disease in children. The etiology of MCDK remains unclear. Given an important role of the renin-angiotensin system in normal kidney development, we explored whether MCDK in children is associated with variants in the genes encoding renin-angiotensin system components by Sanger sequencing. METHODS: The coding regions of...

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Source

Identifiers

PMID: 33173183
DOI: 10.1038/s41390-020-01255-y

Genes

ACE
AGT
AGTR1
REN
IMPACT

Provenance

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