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Article

Human disease-associated mitochondrial mutations fixed in nonhuman primates.

Journal of molecular evolution - 1 Oct 2005

de Magalhães João Pedro

Abstract excerpt

A number of human disease-associated sequences have been reported in other species, such as rodents, but compensatory changes appear to prevent these deleterious mutations from being expressed. The aim of this work was to compare the mitochondrial DNA of multiple primates to ascertain whether mitochondrial disease-causing sequences in humans are fixed in nonhuman primates. Indeed, 46 sequences related to human...

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Identifiers

PMID: 16132471
DOI: 10.1007/s00239-004-0258-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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