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Triangulation of the human, chimpanzee, and Neanderthal genome sequences identifies potentially compensated mutations.

Human mutation - 1 Dec 2010

Zhang Guojie, Pei Zhang, Krawczak Michael, Ball Edward V, Mort Matthew, Kehrer-Sawatzki Hildegard, Cooper David N

Abstract excerpt

Triangulation of the human, chimpanzee, and Neanderthal genome sequences with respect to 44,348 disease-causing or disease-associated missense mutations and 1,712 putative regulatory mutations listed in the Human Gene Mutation Database was employed to identify genetic variants that are apparently...

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Identifiers

PMID: 21064102
DOI: 10.1002/humu.21389

Genes

DUOX2
MAMLD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21064102-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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