Article
Global effects of the small RNA biogenesis machinery on the Arabidopsis thaliana transcriptome.
Proceedings of the National Academy of Sciences of the United States of America - 12 Oct 2010
Laubinger Sascha, Zeller Georg, Henz Stefan R, Buechel Sabine, Sachsenberg Timo, Wang Jia-Wei, Rätsch Gunnar, Weigel Detlef
Abstract excerpt
In Arabidopsis thaliana, four different dicer-like (DCL) proteins have distinct but partially overlapping functions in the biogenesis of microRNAs (miRNAs) and siRNAs from longer, noncoding precursor RNAs. To analyze the impact of different components of the small RNA biogenesis machinery on the transcriptome, we subjected dcl and other mutants impaired in small RNA biogenesis to whole-genome tiling array...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
