Article
Modulation of neuroblastoma cell differentiation by the extracellular matrix.
International journal of cancer - 9 Jul 1992
Matsushima H, Bogenmann E
Abstract excerpt
The effect of a complex in vitro synthesized extracellular matrix (ECM) and its components on growth and phenotypical differentiation of a human neuroblastoma (NB) cell line (HTLA230) was investigated. Rat smooth-muscle-cell (R22CIF)-derived ECM composed of collagen, glycoproteins, and glycosaminoglycans (GAGs) promoted spontaneous neurite outgrowth of HTLA230 cells but did not alter their growth kinetic or...
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