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Article

The effects of EGF-receptor density on multiscale tumor growth patterns.

Journal of theoretical biology - 21 Feb 2006

Athale Chaitanya A, Deisboeck Thomas S

Abstract excerpt

We studied the effects of epidermal growth factor receptor (EGFR) density on tumor growth dynamics, both on the sub- and the multi-cellular level using our previously developed model. This algorithm simulates the growth of a brain tumor using a multi-scale two-dimensional agent-based approach with an integrated transforming growth factor alpha (TGFalpha) induced EGFR-gene-protein interaction network. The results...

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Source

Identifiers

PMID: 16126230
DOI: 10.1016/j.jtbi.2005.06.029

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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