Article
Partner specificity is essential for proper function of the SIX-type homeodomain proteins Sine oculis and Optix during fly eye development.
Developmental biology - 1 Oct 2005
Kenyon Kristy L, Yang-Zhou Donghui, Cai Chuan Qi, Tran Susan, Clouser Chris, Decene Gina, Ranade Swati, Pignoni Francesca
Abstract excerpt
The development of the Drosophila visual system utilizes two members of the highly conserved Six-Homeobox family of transcription factor, Sine oculis and Optix. Although in vitro studies have detected differences in DNA-binding and interactions with some co-factors, questions remain as to what extent the activity for these two transcriptional regulators is redundant or specific in vivo. In this work, we show that...
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