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Article

Six3 and Six6 activity is modulated by members of the groucho family.

Development (Cambridge, England) - 1 Jan 2003

López-Ríos Javier, Tessmar Kristin, Loosli Felix, Wittbrodt Joachim, Bovolenta Paola

Abstract excerpt

Six3 and Six6 are two genes required for the specification and proliferation of the eye field in vertebrate embryos, suggesting that they might be the functional counterparts of the Drosophila gene sine oculis (so). Phylogenetic and functional analysis have however challenged this idea, raising the possibility that the molecular network in which Six3 and Six6 act may be different from that described for SO. To...

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Source

Identifiers

PMID: 12441302
DOI: 10.1242/dev.00185

Genes

SIX3
SIX6
TLE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Six3 and Six6 activity is modulated by members of the groucho family.PMID 12441302Read ↗

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