Article
Methylenetetrahydrofolate reductase C677T polymorphism: association with risk for childhood acute lymphoblastic leukemia and response during the initial phase of chemotherapy in greek patients.
Pediatric blood & cancer - 1 Aug 2006
Chatzidakis Konstantinos, Goulas Antonis, Athanassiadou-Piperopoulou Fani, Fidani Liana, Koliouskas Dimitrios, Mirtsou Vassiliki
Abstract excerpt
BACKGROUND: As of late, a number of studies have focused on the association of the gene for methyletetrahydrofolate reductase (MTHFR) with risk for acute lymphoblastic leukemia (ALL) in children and in adults, as well as with response to chemotherapy. The degree of this association may vary according to the ethnic background and geographic localization of the population under study, or the phase of treatment when...
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