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Article

Epstein-Barr virus infection in vitro can rescue germinal center B cells with inactivated immunoglobulin genes.

Blood - 15 Dec 2005

Chaganti Sridhar, Bell Andrew I, Pastor Noelia Begue, Milner Anne E, Drayson Mark, Gordon John, Rickinson Alan B

Abstract excerpt

Immunoglobulin genotyping of Epstein-Barr virus (EBV)-positive posttransplantation lymphoproliferative disease has suggested that such lesions often arise from atypical post-germinal center B cells, in some cases carrying functionally inactivated immunoglobulin genes. To investigate whether EBV can rescue cells that are failed products of the somatic hypermutation process occurring in germinal centers (GCs), we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16123211
DOI: 10.1182/blood-2005-06-2327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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