Article
Liver fatty acid binding protein gene ablation potentiates hepatic cholesterol accumulation in cholesterol-fed female mice.
American journal of physiology. Gastrointestinal and liver physiology - 1 Jan 2006
Martin Gregory G, Atshaves Barbara P, McIntosh Avery L, Mackie John T, Kier Ann B, Schroeder Friedhelm
Abstract excerpt
Although liver fatty acid binding protein (L-FABP) is postulated to influence cholesterol homeostasis, the physiological significance of this hypothesis remains to be resolved. This issue was addressed by examining the response of young (7 wk) female mice to L-FABP gene ablation and a cholesterol-rich diet. In control-fed mice, L-FABP gene ablation alone induced hepatic cholesterol accumulation (2.6-fold),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
