Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype dependent differential effects of interleukin-1beta and amyloid-beta on viability and cholinergic phenotype of T17 neuroblastoma cells.

Neurochemistry international - 1 Dec 2005

Bielarczyk Hanna, Jankowska-Kulawy Agnieszka, Gul Sylwia, Pawełczyk Tadeusz, Szutowicz Andrzej

Abstract excerpt

Amyloid-beta accumulation in brains of Alzheimer's disease (AD) victims is accompanied by glial inflammatory reactions and preferential loss of cholinergic neurons. Therefore, the aim of this study was to find out whether proinflamatory cytokine interleukin 1beta (IL1beta) modifies effects of amyloid-beta (Abeta) on viability and cholinergic phenotype of septum derived T17 cholinergic neuroblastoma cells. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyl Coenzyme A
Share to Acetylcholine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amyloid beta-Peptides

Share to Brain Neoplasms

Share to Cell Survival

Share to Coloring Agents

Share to Interleukin-1

Share to Neuroblastoma

Source

Identifiers

PMID: 16122837
DOI: 10.1016/j.neuint.2005.06.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype dependent differential effects of interleukin-1beta and amyloid-beta on viability and cholinergic phenotype of T17 neuroblastoma cells.PMID 16122837Read ↗

Phenotype-dependent susceptibility of cholinergic neuroblastoma cells to neurotoxic inputs.Semantic proximity Read ↗

Toxicity of Amyloid-β Peptides Varies Depending on Differentiation Route of SH-SY5Y CellsSemantic proximity Read ↗

Acute and chronic effects of aluminum on acetyl-CoA and acetylcholine metabolism in differentiated and nondifferentiated SN56 cholinergic cells.Semantic proximity Read ↗

Amyloid beta neurotoxicity in the cholinergic but not in the serotonergic phenotype of RN46A cells.Semantic proximity Read ↗

Expression and Localization of AβPP in SH-SY5Y Cells Depends on Differentiation StateSemantic proximity Read ↗

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides.Semantic proximity Read ↗

The cholinergic neuronal phenotype in Alzheimer's disease.Semantic proximity Read ↗

PC12 and THP-1 Cell Lines as Neuronal and Microglia Model in Neurobiological ResearchSemantic proximity Read ↗

Relationships between cholinergic phenotype and acetyl-CoA level in hybrid murine neuroblastoma cells of septal origin.Semantic proximity Read ↗

Quantitative Characterization of Phenotypical Markers After Differentiation of SH-SY5Y Cells.Semantic proximity Read ↗

The effect of differentiation agents on inflammatory and oxidative responses of the human neuroblastoma cell line SK-N-SH.Semantic proximity Read ↗

Cellular mechanisms for amyloid beta-protein activation of rat cholinergic basal forebrain neurons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.