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Article

Phenotype-dependent susceptibility of cholinergic neuroblastoma cells to neurotoxic inputs.

Metabolic brain disease - 1 Sept 2006

Szutowicz A, Bielarczyk H, Gul S, Ronowska A, Pawełczyk T, Jankowska-Kulawy A

Abstract excerpt

A preferential loss of brain cholinergic neurons in the course of Alzheimer's disease and other encephalopathies is accompanied by a proportional impairment of acetyl-CoA synthesizing capacity in affected brains. Particular susceptibility of cholinergic neurons to neurodegeneration might results from insufficient supply of acetyl-CoA for energy production and acetylcholine synthesis in these conditions. Exposure...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16724269
DOI: 10.1007/s11011-006-9007-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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