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Article

Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein.

Virology - 10 Nov 2005

Zheng Yanyan, Fu Xiang-dong, Ou J-H James

Abstract excerpt

The SR-domain protein kinase (SRPK) 1 and 2 are two important kinases involved in cellular RNA splicing. Recently, it was suggested that these two kinases, which could bind to the hepatitis B virus (HBV) core protein, might be the major cellular kinases that phosphorylate the core protein to regulate HBV replication. In this report, we tested the role of SRPK1 and SRPK2 in HBV replication and found that both of...

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Topics

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Share to Hepatitis B virus
Share to Phosphorylation
Share to Protein Serine-Threonine Kinases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to RNA, Viral

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Share to Viral Core Proteins

Share to Virus Assembly

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Source

Identifiers

PMID: 16122776
DOI: 10.1016/j.virol.2005.07.030

Genes

SRPK1
SRPK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein.PMID 16122776Read ↗

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