Article
Clinical outcome and virologic profiles of severe hepatitis B exacerbation due to YMDD mutations.
Journal of hepatology - 1 Nov 2003
Yuen Man-Fung, Kato Takanobu, Mizokami Masashi, Chan Annie On-On, Yuen John Chi-Hang, Yuan He-Jun, Wong Danny Ka-Ho, Sum Siu-Man, Ng Irene Oi-Lin, Fan Sheung-Tat, Lai Ching-Lung
Abstract excerpt
BACKGROUND/AIMS: To study the outcome and the virologic profiles of severe hepatitis exacerbations due to YMDD mutants in lamivudine-treated patients. METHODS: Eighteen lamivudine-treated patients with severe hepatitis exacerbations due to YMDD mutants were recruited. Laboratory and clinical parameters were monitored. Viral genotypes and YMDD mutations were determined. RESULTS: None of the 18 patients had YMDD...
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