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Article

Carbonic anhydrase-related protein VIII deficiency is associated with a distinctive lifelong gait disorder in waddles mice.

Genetics - 1 Nov 2005

Jiao Yan, Yan Jian, Zhao Yu, Donahue Leah Rae, Beamer Wesley G, Li Xinmin, Roe Bruce A, Ledoux Mark S, Gu Weikuan

Abstract excerpt

The waddles (wdl) mouse is a unique animal model that exhibits ataxia and appendicular dystonia without pathological abnormalities of either the central or the peripheral nervous systems. A 19-bp deletion in exon 8 of the carbonic anhydrase-related protein VIII gene (Car8) was detected by high-throughput temperature-gradient capillary electrophoresis heteroduplex analysis of PCR amplicons of genes and ESTs within...

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Identifiers

PMID: 16118194
DOI: 10.1534/genetics.105.044487
PMCID: PMC1456827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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