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Article

Translation elongation factor 1A is essential for regulation of the actin cytoskeleton and cell morphology.

Nature structural & molecular biology - 1 Sept 2005

Gross Stephane R, Kinzy Terri Goss

Abstract excerpt

The binding of eukaryotic translation elongation factor 1A (eEF1A) to actin is a noncanonical function that may link two distinct cellular processes, cytoskeleton organization and gene expression. Using the yeast Saccharomyces cerevisiae, we have established an in vivo assay that directly identifies specific regions and residues of eEF1A responsible for actin interactions and bundling. Using a unique genetic...

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PMID: 16116436
DOI: 10.1038/nsmb979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Translation elongation factor 1A is essential for regulation of the actin cytoskeleton and cell morphology.PMID 16116436Read ↗

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