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Article

eEF1α2 is required for actin cytoskeleton homeostasis in the aging muscle.

Disease models & mechanisms - 1 Sept 2024

Katow Hidetaka, Ryoo Hyung Don

Abstract excerpt

The translation elongation factor eEF1α (eukaryotic elongation factor 1α) mediates mRNA translation by delivering aminoacyl-tRNAs to ribosomes. eEF1α also has other reported roles, including the regulation of actin dynamics. However, these distinct roles of eEF1α are often challenging to uncouple and remain poorly understood in aging metazoan tissues. The genomes of mammals and Drosophila encode two eEF1α...

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Identifiers

PMID: 39207054
DOI: 10.1242/dmm.050729
PMCID: PMC11381931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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