Article
Comparison of the ability of mammalian eEF1A1 and its oncogenic variant eEF1A2 to interact with actin and calmodulin.
Biological chemistry - 1 Jan 2017
Novosylna Oleksandra, Doyle Annette, Vlasenko Dmytro, Murphy Mark, Negrutskii Boris, El'skaya Anna
Abstract excerpt
The question as to why a protein exerts oncogenic properties is answered mainly by well-established ideas that these proteins interfere with cellular signaling pathways. However, the knowledge about structural and functional peculiarities of the oncoproteins causing these effects is far from comp...
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