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Article

Low pH induces co-ordinate regulation of gene expression in oesophageal cells

19 Aug 2005

Abstract excerpt

The development of gastro-oesophageal reflux disease (GORD) is known to be a causative risk factor in the evolution of adenocarcinoma of the oesophagus. The major component of this reflux is gastric acid. However, the impact of low pH on gene expression has not been extensively studied in oesophageal cells. This study utilizes a transcriptomic and bioinformatic approach to assess regulation of gene expression in...

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PMID: 16113055
DOI: 10.1093/carcin/bgi211

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