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Article

Modulation of gene expression by extracellular pH variations in human fibroblasts: A transcriptomic and proteomic study

1 May 2003

Abstract excerpt

Homeostasis of the intracellular ionic concentration, in particular that of hydrogen ions, is pivotal to the maintenance of cell function and viability. Nonetheless, pH fluctuations in both the intracellular and the extracellular compartments can occurr during development, in physiological processes and in disease. The influence of pH variations on gene expression has been studied in different model systems, but...

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PMID: 12748947
DOI: 10.1002/pmic.200300395

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